Ganoderma
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publication ID |
https://doi.org/ 10.1016/j.phytochem.2014.10.010 |
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persistent identifier |
https://treatment.plazi.org/id/03B5EA65-FFF9-FFBF-FE16-FD6A58B820CA |
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treatment provided by |
Felipe |
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scientific name |
Ganoderma |
| status |
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2.1. Ganoderma View in CoL View at ENA database
As a starting point for this study, an extensive literature search was performed to collect structural, as well as available bioactivity information of Ganoderma secondary metabolites.
The genus Ganoderma contains several species which are not easily distinguishable; thus, it is often referred to as a species complex ( Szedlay, 2002). In most cases, reliable species delimitation is only possible by interpretation of morphological–ecological characteristics in combination with molecular phylogenetic data. In literature, a clear identification of species is often neglected. However, traditionally used Ganoderma species (e.g. G. lucidum , Ganoderma applanatum , Ganoderma tsugae ) contain a very similar pattern of constituents (e.g. lanostane-type triterpenes) and therefore the whole genus Ganoderma was considered for evaluation.
This survey led to the generation of a 3D multi-conformational Ganoderma molecular structure database (i.e. Ganoderma DB ) containing a total number of 279 constituents (see Table S 1 View Table 1 in Supporting information; the sd-file of the database is available as Supplementary material). For about 45% of Ganoderma compounds only structural information was collected since no data on biological activity was reported exclusively for these constituents. Concerning structure classes, the Ganoderma DB is mainly composed of lanostane-type triterpenes (97%). This chemical class can be subdivided in 188 triterpene acids and esters, 66 triterpene alcohols and ketones, 3 lanostane peroxides, 2 glycosidic lanostanes, and 7 miscellaneous terpenoids (see Fig. 1 View Fig for examples). Among other scaffolds, 9 long-chain saturated and unsaturated fatty acids and derivatives thereof, one benzofuran and two hydroquinone derivatives are reported as constituents from Ganoderma sp. ( Table S1 View Table 1 ).
No known copyright restrictions apply. See Agosti, D., Egloff, W., 2009. Taxonomic information exchange and copyright: the Plazi approach. BMC Research Notes 2009, 2:53 for further explanation.