Family Theraphosidae Thorell, 1869
Subfamily Schismatothelinae Guadanucci 2014
Type-genus: Schismatothele Karsch 1879 (Guadanucci 2014)
Composition: Euthycaelus Simon 1889, Guyruita Guadanucci et al. 2007, Neoholothele Guadanucci & Weinmann 2015, Schismatothele Karsch 1879, Sickius Soares & Camargo 1948 .
Diagnosis: Schismatothelinae can be distinguished the other Neotropical Theraphosidae by the combination of the following characters: absence of urticating setae, lack of stridulatory organ in the maxillae (lyra), non-dense scopulae, presence of both thickened and clavate trichobothria located on the apical lateral faces of tibiae I-IV, and numerous and dense cuspules on the labium located on a raised area.