Gentiana lutea L. Antimicrobial

Ponticelli, Maria, Lela, Ludovica, Moles, Mariapia, Mangieri, Claudia, Bisaccia, Donatella, Faraone, Immacolata, Falabella, Roberto & Milella, Luigi, 2023, The healing bitterness of Gentiana lutea L., phytochemistry and biological activities: A systematic review, Phytochemistry (113518) 206, pp. 1-27 : 20

3.10. Gentiana lutea L. Antimicrobial activity

Over the years, the excessive and improper use of antibiotics has generated resistance phenomena by pathogens. Therefore, it is necessary to search for undescribed molecules capable of fighting bacterial infections, obviating the problem of resistance. Several studies have reported that G. lutea and its bitter agents exert an antimicrobial action. In this regard, it was observed that the effect of gentian corresponded to that of the antibiotic ampicillin, which is used to treat different gram-positive and negative bacterial infections, including meningitis, endocarditis, salmonellosis, respiratory and urinary tract infections ( Brogden et al., 1979; ˇSavikin et al., 2009b).